The parish lies at the south-easterly; tip of Cornwall land is bounded by water on three sides. With the sea to the south and east and Millbrook Lake (a tidal arm of the River Tamar) to the north, its only neighbours are the parishes of Millbrook and St John.

The parishes of Maker with Rame, St John and Sheviock are collectively known as the Rame Peninsula. Maker with Rame was formed in 1941 by the amalgamation of the ancient parishes of Maker and Rame when they ceased to be viable as separate entities.

The parishes population of 870 registered electors is concentrated in the twin villages of Cawsand and Kingsand which occupy a position, sheltered from the prevailing south-westerlies, on the western shores of Cawsand Bay.